Recombinant Human CLEC-1 Protein

Recombinant Biotinylated Human OX40/TNFRSF4/CD134 Protein (Primary Amine Labeling),hFc Tag性能參數(shù)分子別名（Synonyms）OX40Lreceptor;CD134;TNFRSF4;Ly-70表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）BiotinylatedHumanOX40/TNFRSF4/CD134Protein(PrimaryAmineLabeling)isexpressedfromHEK293withhFctagattheC-Terminus.ItcontainsLeu29-Ala216.[Accession|P43489]分子量大?。∕olecularWeight）TheproteinhasapredictedMWof46.8kDa.Duetoglycosylation,theproteinmigratesto72-75kDabasedonSDS-PAGEresult.（Endotoxin）Lessthan1EUperμgbytheLALmethod.純度（Purity）>95%asdeterminedbySDS-PAGE制劑（Formulation）Suppliedas0.22μmfilteredsolutioninPBS(pH7.4).儲(chǔ)存條件Theproductshouldbestoredat-85~-65℃for1yearfromdateofreceipt.Recommendtoaliquottheproteinintosmallerquantitieswhenfirstusedandavoidrepeatedfreeze-thawcycles.人血清白蛋白（HSA）是脂類等物質(zhì)的轉(zhuǎn)運(yùn)載體，其主要生理功能是調(diào)節(jié)血漿pH值和維持血漿滲透壓。Recombinant Human CLEC-1 Protein,hFc Tag

Recombinant Biotinylated Cynomolgus Siglec-10 Protein,His-Avi Tag性能參數(shù)分子別名（Synonyms）SLG2;SIGLEC10;MGC126774;PRO940表達(dá)區(qū)間及表達(dá)系統(tǒng)（Source）BiotinylatedCynomolgusSiglec-10ProteinisexpressedfromHEK293withHistagandAvitagattheC-terminus.ItcontainsThr17-Asn552.[Accession|A0A2K5WBX8]分子量大?。∕olecularWeight）TheproteinhasapredictedMWof61.71kDa.Duetoglycosylation,theproteinmigratesto72-82kDabasedonSDS-PAGEresult.（Endotoxin）Lessthan1EUperμgbytheLALmethod.純度（Purity）>95%asdeterminedbySDS-PAGE制劑（Formulation）Suppliedas0.22μmfilteredsolutionin25mMMES,150mMNaCl,0.5MArginine(pH5.0).儲(chǔ)存條件Theproductshouldbestoredat-85~-65℃for1yearfromdateofreceipt.Recommendtoaliquottheproteinintosmallerquantitieswhenfirstusedandavoidrepeatedfreeze-thawcycles.Recombinant Human Complement Component C2 Protein,His Tag甲磺酸達(dá)比加群酯是一種抗凝藥，通過(guò)競(jìng)爭(zhēng)結(jié)合凝血酶的纖維蛋白特異結(jié)合位點(diǎn)，從而抑制血栓的形成。

Name:AITRL,MouseSynonyms:Activation-inducedTNFRmemberLigand,TNFSF18,GITRL,TL-6Description:Activation-InducibleTNF-RelatedLigand(AITRL),alsoknownasGlucocorticoid-InducedTNF-RelatedLigand(GITRL),belongstothetumornecrosisfactorsuperfamily(TNFSF).AITRLisaTypeIIsingletransmembraneproteinandshareslowconservationwithintheextracellulardomainwithotherTNFSFmembers.AITRLisexpressedonmacrophages,immatureandmaturedendriticcellsandBcells.Itsreceptor,Activation-InducibleTNFRfamilyReceptor(AITR),isexpressedonTlymphocytes,naturalkiller(NK)cells,andantigen-presentingcells.AfterbindingbyAITRL,AITRcanbereleased.AITRactivationincreasesresistancetotumorsandviralinfectionsandisinvolvedinautoimmuneandinflammatoryprocesses.Inaddition,activatedAITRincreasesTCR-inducedTcellproliferationandcytokineproductionandrescuesTcellsandNKcellsfromapoptosis.RecombinantmouseActivation-InducibleTNF-RelatedLigand(rmAITRL)producedinE.

SARS-CoV-2,whichcausestheglobalpandemiccoronavirusdisease2019(Covid-19),belongstoafamilyofvirusesknownascoronaviruses.TheSARS-CoV-2Sproteinisaglycoproteinthatmediatesmembranefusionandviralentry.TheRBDofSARS-CoV-2bindsametallopeptidase,angiotensin-convertingenzyme2(ACE-2).SeveralemergingSARS-CoV-2genomeshavebeenidentifiedincludingtheOmicron,orB.1.1.529,variant.FirstidentifiedinNovember2021inSouthAfrica,theOmicronvariantquicklybecamethepredominantSARS-CoV-2variantandisconsideredavariantofconcern(VOC).TheOmicronvariantcontains15mutationsinRBDdomainthatpotentiallyaffectviralfitnessandtransmissibility.ThemajorityofthemutationsareinvolvedinACE-2bindingandOmicronbindsACE-2withgreateraffinity,potentiallyexplainingitsincreasedtransmissibility.Severalofthesemutationsarealsoidentifiedinfacilitatingimmuneescapeandreducingneutralizationactivitytoseveralmonoclonalantibodies.然而，在肝臟中，IL-28A誘導(dǎo)的Th1細(xì)胞因子反應(yīng)有助于T細(xì)胞介導(dǎo)的肝炎的炎癥。

Name:4-1BBR/TNFRSF9,Human同義:Tnfrsf9,CD137抗原,T細(xì)胞抗原ILA描述:4-1bb受體,也稱tnfrsf9是tnf超家族受體的一個(gè)成員。它主要表達(dá)在各種T細(xì)胞表面,但也存在于B細(xì)胞、單核細(xì)胞和各種轉(zhuǎn)化細(xì)胞系中。4-1bb受體結(jié)合到4-1bbl,為T(mén)淋巴細(xì)胞提供共同刺激信號(hào)。4-1b受體的信號(hào)傳遞與抗原表達(dá)過(guò)程和細(xì)胞毒性T細(xì)胞的生成有關(guān)。物種:人類資料來(lái)源:E。大腸桿菌生物活性:與標(biāo)準(zhǔn)相比具有完全生物活性。利用人外周血單核細(xì)胞產(chǎn)生的IL8的抑制作用決定了其生物活性。在4-1bb配體和4-1bb受體中,大約90%的IING都是用1g濃度進(jìn)行的。格斯序列縮短:分子式:C終端:分子量:測(cè)量的分子量:大約17.7kda,一個(gè)含有166個(gè)氨基酸的非糖化多肽鏈。Purity:>97%bySDS-PAGEandHPLCanalyses.配方:用10mmPb,PH8.0,150mm納克爾過(guò)濾濃縮液凍干.重建:我們建議在開(kāi)瓶前先將此瓶簡(jiǎn)單離心,以便將其放在底部。在無(wú)菌蒸餾水或含有0.1%BSA的水緩沖液中再形成濃度為0.1-1.0毫克/毫升。庫(kù)存解決方案應(yīng)分配到工作參數(shù)中,并在20℃處儲(chǔ)存。應(yīng)在適當(dāng)?shù)木彌_解決方案中進(jìn)一步稀釋。水平:Lal法測(cè)定的Rhu4-1b受體小于1歐盟/克。儲(chǔ)藏:無(wú)菌過(guò)濾白干凍干粉。α-凝血酶（α-Thrombin）在凝血過(guò)程中起著非常重要的作用，能夠促使纖維蛋白凝塊的產(chǎn)生。Recombinant Cynomolgus CD10/MME Protein,His Tag

在體內(nèi)，活化的X因子（Factor Xa）切割凝血酶原，釋放出活性肽并將凝血酶切割成具有催化活性的α-凝血酶。Recombinant Human CLEC-1 Protein,hFc Tag

產(chǎn)品簡(jiǎn)介凝血酶是由大小分別為31KD和6KD的兩條肽鏈通過(guò)二硫鍵組成的一種絲氨酸蛋白水解酶，可從動(dòng)物血漿中利用已凝血酶原水解制得，可催化纖維蛋白原（fibrinogen）水解釋放A肽和B肽，由此形成纖維蛋白單體，單體進(jìn)一步聚合，在血小板、紅細(xì)胞和白細(xì)胞等參與下形成血凝塊，常用于診斷學(xué)中凝血化驗(yàn)、凝血因子檢測(cè)、血液或血漿的脫纖維化等；另外，由于凝血酶切割序列專一，水解效率高，因此在分子生物學(xué)、生物化學(xué)或生物工程制藥研究中也常作為工具酶用于重組融合蛋白（包含凝血酶識(shí)別位點(diǎn)）的特異性斷裂。本品是從牛的血漿純化制得，具有純度高、比活高、不含有其他蛋白酶活性、滅活病毒、生產(chǎn)穩(wěn)定性好等特點(diǎn)。該酶適切割位點(diǎn)：A-B-Pro-Arg-▼-X-Y（其中，A和B為疏水氨基酸，X和Y為非酸性氨基酸），常見(jiàn)的識(shí)別序列為：1.Leu-Val-Pro-Arg-▼-Gly-Ser。2.Gly-Arg-▼-Gly。產(chǎn)品信息規(guī)格1KU/2KURecombinant Human CLEC-1 Protein,hFc Tag